Testing for Tuberculosis (2024)

Why get tested

Getting tested and treated for TB can protect yourself, your family and friends, and your community.

You may need a TB test if you have:

  • Symptoms of TB disease
    • Spent time with someone who has active TB disease
      • Factors that put you at higher risk of developing active TB disease
        • Employment, school, travel, or immigration health screening requirements

          You may need a TB test even if you do not feel sick. TB germs can live in your body for years without making you feel sick. This is called inactive TB. People with inactive TB do not feel sick and cannot spread TB germs to others.

          Keep Reading:Treating Tuberculosis

          Who should be tested

          If you are at higher risk of being infected with TB germs, you should get tested.

          You have a higher risk of being exposed to TB germs if you:

          • Were born in or frequently travel to countries where TB is common, including some countries in Asia, Africa, and Latin America
            • Live or used to live in large group settings where TB is more common, such as homeless shelters, prisons, or jails
              • Recently spent time with someone who has active TB disease
                • Work in places where TB is more likely to spread, such as hospitals, homeless shelters, correctional facilities, and nursing homes

                  Some people who have inactive TB never develop TB disease, and others with inactive TB develop active TB disease months or even years later when their immune system can no longer keep the TB germs from multiplying and growing in the body.

                  Anyone can get TB, but some people who have inactive TB are more likely to develop TB disease than others.

                  You have a higher risk of developing TB disease once infected if you:

                  • Have a weaker immune system because of certain medications or health conditions such as diabetes, cancer, or HIV
                    • Became infected with TB germs in the last two years
                      • Are a baby or young child, especially under five years of age
                        • Inject illegal drugs
                          • Are sick with other diseases that weaken the immune system
                            • Are elderly
                              • Were not treated correctly for TB in the past

                                TB tests are generally not needed for people with a low risk of infection with TB germs.

                                Keep Reading:Tuberculosis Risk Factors

                                Types of tests

                                There are two types of tests for TB infection: the TB blood test and the TB skin test. Ask your health care provider which TB test is best for you.

                                TB blood test

                                TB blood tests (also called interferon-gamma release assays or IGRAs) use a blood sample to find out if you are infected with TB germs. The tests measure how your immune system reacts when a small amount of your blood is mixed with TB proteins.

                                Tell your health care provider if you received a TB vaccine‎‎

                                Many people born outside the United States have received the TB vaccine (also known as Bacille Calmette-Guérin or BCG).

                                TB blood tests are the preferred test for people who have received the TB vaccine. Unlike the TB skin test, TB blood tests are not affected by BCG vaccination.

                                Keep Reading:Testing for Tuberculosis: Blood Test

                                TB skin test

                                For the TB skin test, a health care provider uses a small needle to put some testing material under the skin. You will need to return to your health care provider in two to three days to see if there is a reaction.

                                Keep Reading:Testing for Tuberculosis: Skin Test

                                Other tests may be needed

                                Your health care provider will do other tests to determine if you have inactive TB or active TB disease if you have a:

                                • Positive TB blood test or TB skin test result
                                  • Negative TB blood test or TB skin test result, but you have symptoms of active TB disease

                                    These tests may include a chest x-ray, and a test of the sputum (phlegm) you cough up.

                                    Keep Reading:Diagnosing Tuberculosis

                                    How to get tested

                                    You can get tested for TB at the health department or at your health care provider's office. Your health care provider will choose the TB test that is best for you. Public and private health care plans may cover TB testing costs.

                                    Finding a test location‎

                                    Contact your state or local TB program about getting tested for TB.

                                    State TB Programs

                                    Understanding TB blood test or TB skin test results

                                    A positive test result for TB infection means you have TB germs in your body. Your health care provider will do other tests to determine if you have inactive TB or active TB disease. These tests may include a chest x-ray, and a test of the sputum (phlegm) you cough up.

                                    A negative test result for TB infection means inactive TB or active TB disease is unlikely, but your health care provider may do more tests, especially if:

                                    • You have symptoms of active TB disease, like coughing, chest pain, fever, weight loss, or tiredness.
                                      • You have HIV.
                                        • You were recently exposed to TB germs.

                                          Keep Reading:Diagnosing Tuberculosis

                                          What to do if you've tested positive

                                          If your TB blood test or TB skin test is positive, you have TB germs in your body. Your health care provider will do other tests to determine if you have inactive TB or active TB disease.

                                          Keep a record of your positive test result‎

                                          Once you have a positive TB blood test or TB skin test result, you may still have a positive test result on future TB tests. This includes even after you finish taking all of your TB medicine for inactive TB or active TB disease.

                                          Ask your health care provider for a written record of your positive TB test result. This will be helpful if you are asked to have another TB test in the future.

                                          Keep Reading:Diagnosing Tuberculosis

                                          Resources

                                          What You Need to Know About Tuberculosis Fact Sheet

                                          Use this fact sheet to learn basic information about tuberculosis (TB).

                                          Questions and Answers About Tuberculosis Booklet

                                          Questions and Answers About TB has information on inactive TB and TB disease.

                                          What You Need to Know About the TB Skin Test Fact Sheet

                                          Learn what to expect when getting a TB skin test.

                                          Testing for Tuberculosis (2024)

                                          FAQs

                                          How do they test for tuberculosis? ›

                                          TB blood tests (also called interferon-gamma release assays or IGRAs) use a blood sample to find out if you are infected with TB germs. The tests measure how your immune system reacts when a small amount of your blood is mixed with TB proteins.

                                          Which test confirms tuberculosis? ›

                                          The tuberculosis (TB) blood test, also called an Interferon Gamma Release Assay or IGRA, is a way to find out if you have TB germs in your body. The TB blood test can be done instead of a TB skin test (Mantoux). There are two kinds of TB blood tests: QuantiFERON®-TB.

                                          What is the most common screening test for tuberculosis? ›

                                          You will have either be a TB skin test or a TB blood test, depending on your health and medical history. TB skin tests are used more often, but blood tests for TB are becoming more common. For a TB skin test (also called a Mantoux tuberculin skin test), you will need two visits to complete the test.

                                          How is TB usually diagnosed? ›

                                          There are two kinds of screening tests for TB: the Mantoux tuberculin skin test (TST) and the blood test, called the interferon gamma release assay (IGRA). For the TST, a healthcare provider will inject a small amount of a substance called purified protein derivative (PPD) under the skin of your forearm.

                                          How do you confirm if you have TB? ›

                                          A health care provider may diagnose you with inactive TB or active TB disease based on your:
                                          1. Medical history.
                                          2. Physical examination.
                                          3. Test for TB infection (TB blood test or TB skin test)
                                          4. Chest x-ray.
                                          5. Laboratory tests to see if TB germs are present (sputum smear and culture)
                                          6. Laboratory tests for drug resistance.
                                          Apr 22, 2024

                                          Is it hard to detect tuberculosis? ›

                                          In its early stages or when it's latent, TB can be difficult to detect on a chest X-ray. Even if nothing remarkable appears on your X-ray and you have no symptoms, you may still have TB bacteria in your body. Only a skin or blood test can detect it.

                                          Does tuberculosis go away? ›

                                          Tuberculosis symptoms can seem to go away, but the illness often reactivates. Without treatment, tuberculosis can return. Tuberculosis treatment regimens last for months. Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis bacteria that usually affects the lungs.

                                          How contagious is tuberculosis? ›

                                          Although it is spread in a similar way to a cold or the flu, TB is not as contagious. You would usually have to spend prolonged periods in close contact with an infected person to catch the infection yourself. For example, TB infections usually spread between family members who live in the same house.

                                          What is the golden diagnostic test for TB? ›

                                          There is no gold standard method for diagnosing TB infection [5]. The World Health Organization (WHO) currently recommends a tuberculin skin test (TST) or an interferon-γ release assay (IGRA) to test for TB infection [6].

                                          What is the mandatory test for tuberculosis? ›

                                          There are two tests that are used to determine if a person has been infected with TB bacteria: TB blood tests (Interferon Gamma Release Assay [IGRA]) and the TB skin test (Mantoux tuberculin skin test).

                                          What happens if I test positive for TB? ›

                                          TB germs can live in your body for years without causing symptoms. Without treatment, inactive TB can develop into active TB disease and make you sick. If you have been diagnosed with active TB disease, you will need to take and finish all your TB medicine.

                                          What are the odds of getting TB after exposure? ›

                                          Between 20 to 30% of people exposed to a person with active TB become infected. For that reason, doctors usually distinguish between infection (or a positive TB test) and an active infection. After you are infected, your immune system will attack the bacteria.

                                          What are the early warning signs of tuberculosis? ›

                                          Important to recognise tuberculosis (TB) symptoms early
                                          • persistent and lengthy coughing.
                                          • fever and night sweats.
                                          • unexplained weight loss.
                                          • blood in your sputum (phlegm or spit) at any time.
                                          • a lack of appetite.
                                          • fatigue.
                                          • a general sense of feeling unwell.
                                          Mar 22, 2024

                                          How long can you have TB without knowing? ›

                                          TB germs are dormant (asleep) in your body. This phase can last for a very long time - even decades. TB germs are reproducing and spreading in your body, causing tissue damage. You don't look or feel sick.

                                          What is the fastest way to diagnose TB? ›

                                          Sputum tests

                                          Your health care provider may take a sample of the mucus that comes up when you cough, also called sputum. If you have active TB disease in your lungs or voice box, lab tests can detect the bacteria. A relatively quick laboratory test can tell if the sputum likely has the TB bacteria.

                                          Is A TB test Painful? ›

                                          Does a TB test hurt? For both a TB skin test and blood test, you may feel a small pinch from the needle, but this will be brief. For a skin TB test, the liquid the healthcare provider injects should not burn or feel uncomfortable.

                                          Is TB curable permanently? ›

                                          Tuberculosis (TB) can be completely cured with the right treatment. Your doctor and health care team will be there to help you every step of the way. The key to a successful recovery is following the treatment as prescribed and communicating any questions and concerns with your doctor.

                                          How long is TB contagious? ›

                                          If you are diagnosed with pulmonary TB, you will be contagious up to about 2 to 3 weeks into your course of treatment. You will not normally need to be isolated during this time, but it's important to take some basic precautions to stop TB spreading to your family and friends.

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